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Sourced from United Kingdom
Prescription Required
Generic Equivalents what's the difference?
Agomelatine (Generic)
Sourced from United Kingdom
Prescription Required

Valdoxan (Agomelatine)

Valdoxan contains the active ingredient agomelatine. It belongs to a group of medicines called antidepressants. You have been given Valdoxan to treat your depression. Valdoxan is used in adults.

Depression is a continuing disturbance of mood that interferes with everyday life. The symptoms of depression vary from one person to another, but often include deep sadness, feelings of worthlessness, loss of interest in favourite activities, sleep disturbances, feeling of being slowed down, feelings of anxiety, changes in weight.

The expected benefits of Valdoxan are to reduce and gradually remove the symptoms related to your depression.

Warnings and Precautions

Do not take Valdoxan if:

  • you are allergic to agomelatine or any of the other ingredients of this medicine
  • your liver does not work properly (hepatic impairment).
  • you are taking fluvoxamine (another medicine used in the treatment of depression) or ciprofloxacin (an antibiotic).

There could be some reasons why Valdoxan may not be suitable for you:

  • If you are taking medicines known to affect the liver. Ask your doctor for advice on which medicine that is.
  • If you are obese or overweight, ask your doctor for advice.
  • If you are diabetic, ask your doctor for advice.
  • If you have increased levels of liver enzymes before treatment, your doctor will decide if Valdoxan is right for you.
  • If you have bipolar disorder, have experienced or if you develop manic symptoms (a period of abnormally high excitability and emotions) talk to your doctor before you start taking this medicine or before you continue with this medicine (see also under “Possible side effects” in section 4).
  • If you are suffering from dementia, your doctor will make an individual evaluation of whether it is right for you to take Valdoxan.

Other Medicines and Valdoxan

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

You should not take Valdoxan together with certain medicines:  fluvoxamine (another medicine used in the treatment of depression), ciprofloxacin (an antibiotic) can modify the expected dose of agomelatine in your blood.

Make sure to tell your doctor if you are taking any of the following medicines: propranolol (a beta-blocker used in the treatment of hypertension), enoxacin (antibiotic).

Make sure to tell your doctor if you are smoking more than 15 cigarettes/day.

It is not advisable to drink alcohol while you are being treated with Valdoxan.

How To Take Valdoxan

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

Valdoxan is for oral use. You should swallow your tablet with a drink of water. Valdoxan can be taken with or without food.

If you have taken more Valdoxan than you should, or if for example a child has taken medicine by accident, contact your doctor immediately.

The experience of overdoses with Valdoxan is limited but reported symptoms include pain in the upper part of the stomach, somnolence, fatigue, agitation, anxiety, tension, dizziness, cyanosis or malaise.

If You Forget To Take Valdoxan

Do not take a double dose to make up for a forgotten dose. Just carry on with the next dose at the usual time.

If You Stop Taking Valdoxan

Do not stop taking your medicine without the advice of your doctor even if you feel better.

If you have any further questions on the use of this product, please ask your doctor or pharmacist.

Possible Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Most side effects are mild or moderate. They usually occur within the first two weeks of the treatment and are usually temporary.

These side effects include:

Very common side effects (may affect more than 1 in 10 people): headache.

Common side effects (may affect up to 1 in 10 people): dizziness, sleepiness (somnolence), difficulty in sleeping (insomnia), feeling sick (nausea), diarrhoea, constipation, abdominal pain, back pain, tiredness, anxiety, abnormal dreams, increased levels of liver enzymes in your blood, vomiting, weight increased.

Uncommon side effects (may affect up to 1 in 100 people): migraine, pins and needles in the fingers and toes (paraesthesia), blurred vision, restless legs syndrome (a disorder that is characterised by an uncontrollable urge to move the legs), ringing in the ears, excessive sweating (hyperhidrosis), eczema, pruritus, urticaria (hives), agitation, irritability, restlessness, aggressive behaviour, nightmares, mania/hypomania (see also under “Warnings and precautions” in section 2), suicidal thoughts or behaviour, confusion, weight decreased.

Rare side effects (may affect up to 1 in 1,000 people): serious skin eruption (erythematous rash), face oedema (swelling) and angioedema (swelling of the face, lips, tongue and/or throat that may cause difficulty in breathing or swallowing), hepatitis, yellow coloration of the skin or the whites of the eyes (jaundice), hepatic failure*, hallucinations, inability to remain still (due to physical and mental unrest), inability to completely empty the bladder.

* Few cases resulting in liver transplantation or death have been reported.

If you have any questions about buying discount Valdoxan online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists by calling 1-833-313-3173.

Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


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